CHEMBL562384


SMILES Cc1cc2nc(C)c(CN3CCN(c4ccccn4)CC3)n2c(C)n1
InChIKey URKAJHJBVOPDPZ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 336.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.66 4.66 4.66 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.92 6.92 6.92 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.19 6.19 6.19 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.77 4.88 5.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.19 6.19 6.19 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database