CHEMBL64288
SMILES | COc1ccc(Br)cc1-c1nc(CN2CCN(c3ccccc3)CC2)co1 |
InChIKey | TYIIYIRHCHVCLI-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 0 |
Rotatable bonds | 5 |
Molecular weight (Da) | 427.1 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D4 | DRD4 | Human | Dopamine | A | pKi | 6.43 | 6.43 | 6.43 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 6.18 | 6.18 | 6.18 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 6.16 | 6.32 | 6.48 | ChEMBL |
D1 | DRD1 | Bovine | Dopamine | A | pKi | 5.31 | 5.31 | 5.31 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |