D-GLUTAMATE


SMILES N[C@H](CCC(=O)O)C(=O)O
InChIKey WHUUTDBJXJRKMK-GSVOUGTGSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 147.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Rat Metabotropic glutamate C pKi 5.0 5.0 5.0 PDSP Ki database
mGlu8 GRM8 Rat Metabotropic glutamate C pKi 5.0 5.0 5.0 PDSP Ki database
mGlu2 GRM2 Human Metabotropic glutamate C pKi 5.0 5.0 5.0 PDSP Ki database
mGlu3 GRM3 Human Metabotropic glutamate C pKi 5.0 5.0 5.0 PDSP Ki database
mGlu6 GRM6 Rat Metabotropic glutamate C pKi 5.0 5.0 5.0 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu6 GRM6 Rat Metabotropic glutamate C pEC50 4.7 4.7 4.7 ChEMBL
mGlu4 GRM4 Rat Metabotropic glutamate C pEC50 4.92 4.92 4.92 ChEMBL
mGlu3 GRM3 Rat Metabotropic glutamate C pEC50 5.05 5.05 5.05 ChEMBL
mGlu1 GRM1 Rat Metabotropic glutamate C pEC50 5.0 5.0 5.0 ChEMBL
mGlu2 GRM2 Rat Metabotropic glutamate C pEC50 5.4 5.4 5.4 ChEMBL
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 5.35 5.35 5.35 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pEC50 5.36 5.36 5.36 ChEMBL