CHEMBL76402


SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(Br)cc(OC)c1OC
InChIKey WGLPSCZHULDZSS-JTQLQIEISA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 386.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Pig Dopamine A pKi 4.82 4.82 4.82 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.68 6.68 6.68 ChEMBL
D2 DRD2 Rat Dopamine A pKi 10.19 10.19 10.19 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.38 9.38 9.38 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.8 9.0 9.19 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 8.85 8.85 8.85 ChEMBL