CHEMBL563109
SMILES | COc1ccccc1N1CCN(Cc2cnc3cc(C)nc(C)n23)CC1 |
InChIKey | VGIPYYQGXWSQEJ-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 6 |
Hydrogen bond donors | 0 |
Rotatable bonds | 4 |
Molecular weight (Da) | 351.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D1 | DRD1 | Bovine | Dopamine | A | pKi | 4.96 | 4.96 | 4.96 | ChEMBL |
D4 | DRD4 | Human | Dopamine | A | pKi | 7.18 | 7.18 | 7.18 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 5.82 | 5.82 | 5.82 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 5.89 | 6.06 | 6.24 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 5.89 | 6.06 | 6.24 | PDSP Ki database |
D3 | DRD3 | Human | Dopamine | A | pKi | 5.82 | 5.82 | 5.82 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |