CHEMBL80366


SMILES C[C@H](N)CN1CCc2cc(F)c(Cl)cc21
InChIKey OKTLNQVSINRJKA-ZETCQYMHSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 228.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.51 7.51 7.51 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.85 7.85 7.85 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.78 6.78 6.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 8.14 8.14 8.14 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.51 7.51 7.51 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.43 6.43 6.43 ChEMBL