CHEMBL8224


SMILES CCc1cc(OC)c(CC(C)N)cc1OC
InChIKey HXJKWPGVENNMCC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 223.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 ChEMBL
5-HT2C K7GSR7 Pig 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 PDSP Ki database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.41 5.41 5.41 PDSP Ki database
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pKi 5.61 5.61 5.61 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.28 7.28 7.28 PDSP Ki database
β2 ADRB2 Human Adrenoceptors A pKi 5.1 5.1 5.1 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database