CHEMBL56843


SMILES O=C(CCCN1CCC(c2ccccc2)CC1)c1ccc(F)cc1
InChIKey GOPOBAVSYNADGN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 325.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKd 8.1 8.1 8.1 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.11 8.11 8.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Rat Dopamine A pIC50 5.12 5.12 5.12 ChEMBL
D2 DRD2 Rat Dopamine A pIC50 7.16 7.16 7.16 ChEMBL