CHEMBL70676


SMILES Ic1c(NC2=NCCN2)ccc2nccnc12
InChIKey YYTGOWDNUUXBGS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 339.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 5.72 5.72 5.72 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 6.55 6.55 6.55 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 7.37 7.37 7.37 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.39 6.39 6.39 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.01 6.01 6.01 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 8.17 8.17 8.17 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pEC50 7.26 7.26 7.26 ChEMBL
α2A ADA2A Human Adrenoceptors A pEC50 7.94 7.94 7.94 ChEMBL