CHEMBL84931


SMILES CN(C)CC1CC2c3ccccc3Cc3ccc(F)cc3N2O1
InChIKey MSQRTETUBFIHMP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 312.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 6.52 6.52 6.52 ChEMBL
α2C ADA2C Human Adrenoceptors A pIC50 5.93 5.93 5.93 ChEMBL
α1A ADA1A Human Adrenoceptors A pIC50 7.35 7.35 7.35 ChEMBL
α2A ADA2A Human Adrenoceptors A pIC50 6.3 6.3 6.3 ChEMBL
H1 HRH1 Human Histamine A pIC50 8.59 8.59 8.59 ChEMBL
D4 DRD4 Human Dopamine A pIC50 7.84 7.84 7.84 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 8.94 8.94 8.94 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pIC50 5.8 5.8 5.8 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 8.94 8.94 8.94 ChEMBL
D3 DRD3 Human Dopamine A pIC50 7.85 7.85 7.85 ChEMBL
D2 DRD2 Human Dopamine A pIC50 7.44 7.44 7.44 ChEMBL