CHEMBL570863


SMILES Cc1ccccc1C(C)OC1=NCCN1
InChIKey NGYGSYPEYBVPQK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 204.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.57 6.57 6.57 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.57 6.57 6.57 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 7.61 7.61 7.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pEC50 5.3 5.3 5.3 ChEMBL
α2C ADA2C Human Adrenoceptors A pEC50 7.2 7.2 7.2 ChEMBL