CHEMBL88289


SMILES FC(F)(F)c1nc2c(N3CCN(Cc4ccccc4)CC3)cccc2[nH]1
InChIKey PSWUORNVMIRUSW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 360.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.54 8.54 8.54 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.48 8.88 9.29 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.83 7.83 7.83 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.39 8.39 8.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database