CHEMBL75491


SMILES Cc1c(Nc2ncc[nH]2)ccc2nccnc12
InChIKey AEWIKTWIKIWVNJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 225.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 7.51 7.51 7.51 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.47 6.47 6.47 ChEMBL
α2B ADA2B Rat Adrenoceptors A pKi 5.92 5.92 5.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database