NOCODAZOLE


SMILES COC(=O)Nc1nc2ccc(C(=O)c3cccs3)cc2[nH]1
InChIKey KYRVNWMVYQXFEU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 301.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 4.89 4.89 4.89 ChEMBL
A2A AA2AR Human Adenosine A pKi 5.38 5.38 5.38 ChEMBL
A1 AA1R Human Adenosine A pKi 4.53 4.53 4.53 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 4.7 4.7 4.7 ChEMBL
A2A AA2AR Human Adenosine A pIC50 5.12 5.12 5.12 ChEMBL
A1 AA1R Human Adenosine A pIC50 4.3 4.3 4.3 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 6.4 6.4 6.4 ChEMBL
NPS NPSR1 Human Neuropeptide S A Potency 6.0 6.0 6.0 ChEMBL