PROCYCLIDINE


SMILES OC(CCN1CCCC1)(c1ccccc1)C1CCCCC1
InChIKey WYDUSKDSKCASEF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 287.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.34 8.34 8.34 PDSP Ki database
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.6 7.6 7.6 PDSP Ki database
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 7.91 7.91 7.91 PDSP Ki database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.15 8.23 8.32 PDSP Ki database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 7.62 7.62 7.62 PDSP Ki database
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 7.37 7.37 7.37 PDSP Ki database
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 8.35 8.35 8.35 PDSP Ki database
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 8.14 8.14 8.14 PDSP Ki database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.08 8.08 8.08 Drug Central
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.12 8.12 8.12 Drug Central
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.1 8.1 8.1 Drug Central
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.09 8.09 8.09 Drug Central
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.12 8.12 8.12 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pIC50 5.17 5.17 5.17 ChEMBL
H1 HRH1 Human Histamine A pIC50 4.75 4.75 4.75 ChEMBL
H1 HRH1 Rat Histamine A pIC50 8.29 8.29 8.29 Drug Central