CHEMBL593103


SMILES CN1CCN(c2cc(NCc3ccc(F)cc3)nc(N)n2)CC1
InChIKey ZPAHWVAWJGJPSL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 316.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 7.34 7.36 7.37 ChEMBL
H3 HRH3 Human Histamine A pKi 6.49 6.49 6.49 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 7.04 7.36 7.68 ChEMBL