CHEMBL594721


SMILES CN1CCN(c2cc(NCc3ccccc3Cl)nc(N)n2)CC1
InChIKey FWRAMRVPMYVJMR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 332.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 7.75 7.76 7.77 ChEMBL
H3 HRH3 Human Histamine A pKi 6.46 6.46 6.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 7.71 7.96 8.22 ChEMBL