CHEMBL596527


SMILES Cn1c(CN2CCC(c3nsc4ccccc34)CC2)nc2ccccc21
InChIKey HYGJPVUOYCSNGB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 362.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 5.4 5.4 5.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.1 7.1 7.1 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.7 6.7 6.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu2 GRM2 Human Metabotropic glutamate C pEC50 5.6 6.15 6.7 ChEMBL