CHEMBL1197251


SMILES O=C(O[C@H]1C[N+]2(CCc3ccccc3)CCC1CC2)C(O)(c1cccs1)c1cccs1
InChIKey XQODGRWXBOXGGN-WRDKKKNXSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 454.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 10.1 10.1 10.1 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 10.1 10.1 10.1 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 10.1 10.1 10.1 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M2 ACM2 Human Acetylcholine (muscarinic) A pIC50 9.74 9.74 9.74 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pIC50 9.85 9.85 9.85 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pIC50 8.57 9.13 9.7 ChEMBL