(S)-α-methylhistamine


SMILES C[C@@H](Cc1cnc[nH]1)N
InChIKey XNQIOISZPFVUFG-YFKPBYRVSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 125.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pKi 5.79 6.46 7.2 ChEMBL
H3 HRH3 Human Histamine A pKi 7.6 7.6 7.6 Guide to Pharmacology
H4 HRH4 Human Histamine A pKi 5.4 5.4 5.4 ChEMBL
H4 HRH4 Human Histamine A pKi 5.5 5.5 5.5 Guide to Pharmacology
H3 HRH3 Rat Histamine A pKi 6.6 6.6 6.6 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Human Histamine A pEC50 8.0 8.0 8.0 ChEMBL
H4 HRH4 Human Histamine A pEC50 4.9 4.9 4.9 ChEMBL