CHEMBL606547


SMILES CN1CCC[C@@H]1Cc1c[nH]c2ccc(NS(=O)(=O)c3ccccc3Cl)cc12
InChIKey JEYKBVBGFCMXAB-MRXNPFEDSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 403.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 7.8 7.8 7.8 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.82 7.82 7.82 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 7.53 7.53 7.53 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.13 7.13 7.13 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.54 6.54 6.54 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.43 6.43 6.43 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.77 6.77 6.77 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pEC50 8.96 8.96 8.96 ChEMBL