CHEMBL2096742
SMILES | CCCC[C@@H](NC(C)=O)C(=O)N[C@@H]1CC(=O)NCCCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O |
InChIKey | GGYWLZFXFKFWKL-GLWNXGLNSA-N |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Protein |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
MC3 | MC3R | Human | Melanocortin | A | pKd | 8.3 | 8.57 | 8.7 | ChEMBL |
MC4 | MC4R | Human | Melanocortin | A | pKd | 9.1 | 9.17 | 9.3 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
MC5 | MC5R | Mouse | Melanocortin | A | pEC50 | 8.64 | 8.64 | 8.64 | ChEMBL |
MC1 | MSHR | Mouse | Melanocortin | A | pEC50 | 9.19 | 9.19 | 9.19 | ChEMBL |
MC1 | MSHR | Human | Melanocortin | A | pEC50 | 8.82 | 9.63 | 10.44 | ChEMBL |
MC1 | MSHR | Human | Melanocortin | A | pIC50 | 9.0 | 9.0 | 9.0 | ChEMBL |
MC5 | MC5R | Human | Melanocortin | A | pEC50 | 8.92 | 9.42 | 9.92 | ChEMBL |
MC5 | MC5R | Human | Melanocortin | A | pIC50 | 9.05 | 9.55 | 10.05 | ChEMBL |
MC3 | MC3R | Human | Melanocortin | A | pIC50 | 8.48 | 8.92 | 9.64 | ChEMBL |
MC4 | MC4R | Human | Melanocortin | A | pIC50 | 8.74 | 9.39 | 10.22 | ChEMBL |