CHEMBL2096742


SMILES CCCC[C@@H](NC(C)=O)C(=O)N[C@@H]1CC(=O)NCCCC[C@@H](C(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O
InChIKey GGYWLZFXFKFWKL-GLWNXGLNSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC3 MC3R Human Melanocortin A pKd 8.3 8.57 8.7 ChEMBL
MC4 MC4R Human Melanocortin A pKd 9.1 9.17 9.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pEC50 8.64 8.64 8.64 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 9.19 9.19 9.19 ChEMBL
MC1 MSHR Human Melanocortin A pEC50 8.82 9.63 10.44 ChEMBL
MC1 MSHR Human Melanocortin A pIC50 9.0 9.0 9.0 ChEMBL
MC5 MC5R Human Melanocortin A pIC50 9.05 9.55 10.05 ChEMBL
MC5 MC5R Human Melanocortin A pEC50 8.92 9.42 9.92 ChEMBL
MC3 MC3R Human Melanocortin A pIC50 8.48 8.92 9.64 ChEMBL
MC4 MC4R Human Melanocortin A pIC50 8.74 9.39 10.22 ChEMBL