CHEMBL342252


SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CC(C)C)C(=O)O
InChIKey DQDBCHHEIKQPJD-CSJNAZMVSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NTS1 NTR1 Mouse Neurotensin A pKi 9.28 10.25 10.74 ChEMBL
NTS2 NTR2 Rat Neurotensin A pKi 7.48 7.48 7.48 ChEMBL
NTS2 NTR2 Human Neurotensin A pKd 8.85 8.85 8.85 ChEMBL
NTS1 NTR1 Human Neurotensin A pKd 9.1 9.29 9.8 ChEMBL
NTS1 NTR1 Human Neurotensin A pKi 8.98 9.43 9.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NTS2 NTR2 Rat Neurotensin A pIC50 8.27 8.27 8.27 ChEMBL
NTS1 NTR1 Rat Neurotensin A pIC50 8.0 8.0 8.0 ChEMBL
NTS1 NTR1 Rat Neurotensin A pEC50 11.0 11.0 11.0 ChEMBL
NTS2 NTR2 Human Neurotensin A pIC50 8.57 8.57 8.57 ChEMBL
NTS1 NTR1 Human Neurotensin A pIC50 8.85 9.18 9.52 ChEMBL
NTS1 NTR1 Human Neurotensin A pEC50 9.0 9.0 9.0 ChEMBL