TRIAZOLAM


SMILES Cc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2
InChIKey JOFWLTCLBGQGBO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 342.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Human Platelet-activating factor A pKi 5.6 5.88 6.16 PDSP Ki database
PAF PTAFR Human Platelet-activating factor A pKi 8.23 8.23 8.23 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Guinea pig Platelet-activating factor A pIC50 4.96 4.96 4.96 ChEMBL
CCK1 CCKAR Rat Cholecystokinin A pIC50 4.41 4.41 4.41 ChEMBL
CCK1 CCKAR Rat Cholecystokinin A pIC50 8.36 8.36 8.36 Drug Central