ALPRAZOLAM


SMILES Cc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2
InChIKey VREFGVBLTWBCJP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 308.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 5.0 5.0 5.0 PDSP Ki database
PAF PTAFR Human Platelet-activating factor A pKi 5.33 5.46 5.58 PDSP Ki database
PAF PTAFR Human Platelet-activating factor A pKi 8.26 8.26 8.26 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
PAF PTAFR Guinea pig Platelet-activating factor A pIC50 4.66 4.66 4.66 ChEMBL
CCK1 CCKAR Rat Cholecystokinin A pIC50 4.19 4.19 4.19 ChEMBL
CCK1 CCKAR Rat Cholecystokinin A pIC50 8.38 8.38 8.38 Drug Central