(-)-trans-H2-PAT


SMILES CN([C@H]1Cc2ccccc2[C@@H](C1)c1ccccc1)C
InChIKey DXJUCAUQIHNOAF-WMZOPIPTSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 251.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.33 6.33 6.33 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.62 6.62 6.62 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.37 6.37 6.37 ChEMBL
H1 HRH1 Human Histamine A pKi 8.6 8.7 8.8 Guide to Pharmacology
H3 HRH3 Human Histamine A pKi 7.52 7.52 7.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database