MEDROXYPROGESTERONE ACETATE


SMILES CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C
InChIKey PSGAAPLEWMOORI-PEINSRQWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 2
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pKi 4.56 4.56 4.56 ChEMBL
H2 HRH2 Human Histamine A pKi 8.34 8.34 8.34 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pIC50 4.55 4.55 4.55 ChEMBL
NPS NPSR1 Human Neuropeptide S A Potency 5.6 5.6 5.6 ChEMBL