CHEMBL73392


SMILES Brc1c(NC2=NCCS2)ccc2nccnc12
InChIKey KSVHJUZGYJOCLG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 308.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 4.22 4.22 4.22 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 4.56 4.56 4.56 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 4.76 4.76 4.76 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 4.55 4.55 4.55 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 4.67 4.67 4.67 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 4.99 4.99 4.99 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pEC50 5.56 5.56 5.56 ChEMBL