CHEMBL74114


SMILES CS(=O)(=O)c1cccc(F)c1NCC1=NCCN1
InChIKey FAINGUBYHMRNKU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 271.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.42 6.42 6.42 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 6.04 6.04 6.04 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.16 6.16 6.16 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.38 6.38 6.38 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.06 6.06 6.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2C ADA2C Human Adrenoceptors A pEC50 6.35 6.35 6.35 ChEMBL
α1A ADA1A Human Adrenoceptors A pEC50 7.38 7.38 7.38 ChEMBL