CHEMBL86060


SMILES c1ccc(C2=N[C@@H](CN3CCN(c4ccccc4)CC3)CO2)cc1
InChIKey JFMAZBIWGGSVJX-SFHVURJKSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 321.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.01 5.21 5.4 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.39 6.43 6.47 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.48 5.82 6.16 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.77 6.09 6.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database