JNJ-39319202


SMILES CCN1CCN(CC1)c1cccc2c1CN(C2=O)[C@@H](c1ccc(c(c1)OC)OC)CCCNS(=O)(=O)c1cccs1
InChIKey MWCLCGKVMLYVJI-RUZDIDTESA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 12
Molecular weight (Da) 598.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
UT UR2R Human Urotensin A pKi 8.4 8.4 8.4 ChEMBL
UT UR2R Human Urotensin A pKi 8.4 8.4 8.4 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
UT UR2R Human Urotensin A pIC50 8.1 8.1 8.1 ChEMBL
UT UR2R Rat Urotensin A pIC50 9.0 9.0 9.0 ChEMBL