Diphenylpyraline


SMILES CN1CCC(CC1)OC(C2=CC=CC=C2)C3=CC=CC=C3
InChIKey OWQUZNMMYNAXSL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 281.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pKi 8.49 8.49 8.49 PDSP Ki database
H1 HRH1 Human Histamine A pKi 8.32 8.32 8.32 PDSP Ki database
H1 HRH1 Guinea pig Histamine A pKi 8.51 8.51 8.51 PDSP Ki database
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 8.11 8.11 8.11 Drug Central
H1 HRH1 Human Histamine A pKi 8.09 8.09 8.09 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database