CHEMBL97596


SMILES O=S(=O)(Nc1ccc2nccc(N3CCNCC3)c2c1)c1ccc2c(Cl)cccc2c1
InChIKey XOEZEACRWZTMQK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 452.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 6.2 6.2 6.2 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 5.6 5.6 5.6 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 9.0 9.0 9.0 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.6 5.6 5.6 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.8 6.8 6.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database