(3S)-3-(((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-yl)methylamino)methyl)-7,9-dihydro-2H-[1,4]dioxino[2,3-e]indol-8(3H)-one


SMILES C1CC2=C(CC1CNCC3COC4=C(O3)C=CC5=C4CC(=O)N5)C6=C(N2)C=CC(=C6)F
InChIKey SDLSVMUKJMMARH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 4
Molecular weight (Da) 421.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 PDSP Ki database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.89 7.55 8.22 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 8.52 8.52 8.52 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database