SULPIRIDE,(-)


SMILES CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC
InChIKey BGRJTUBHPOOWDU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 341.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT2C K7GSR7 Pig 5-Hydroxytryptamine A pKi 5.0 5.04 5.14 PDSP Ki database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
BB3 BRS3 Human Bombesin A pKi 5.0 5.16 5.32 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 5.26 7.31 8.3 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.32 7.73 8.19 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 5.7 6.56 7.7 PDSP Ki database
D3 DRD3 Rat Dopamine A pKi 6.37 7.18 8.1 PDSP Ki database
D2 DRD2 Rat Dopamine A pKi 5.0 7.22 8.6 PDSP Ki database
D1 DRD1 Rat Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
D5 DRD5 Human Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
D1 DRD1 Human Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
D4 DRD4 Rat Dopamine A pKi 5.0 6.14 7.28 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database