5-HT,N-ACETYL


SMILES CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2
InChIKey SOYKEARSMXGVTM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 274.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 5.14 5.23 5.38 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
H1 HRH1 Human Histamine A pKi 7.52 8.06 8.57 PDSP Ki database
H1 HRH1 Rat Histamine A pKi 8.1 8.1 8.1 PDSP Ki database
H1 HRH1 Guinea pig Histamine A pKi 8.7 8.93 9.16 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database