WY 27127


SMILES CS(=O)(=O)NCCN(C1CCN2CCC3=CC=CC=C3C2C1)S(=O)(=O)C
InChIKey VSQCTWPNMPWYSD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 401.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 7.96 7.96 7.96 PDSP Ki database
α2C ADA2C Human Adrenoceptors A pKi 9.25 9.25 9.25 PDSP Ki database
α2B ADA2B Rat Adrenoceptors A pKi 8.28 8.28 8.28 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database