2-(2-chlorophenyl)-1-(4-chlorophenyl)-N-((1R,2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)-1H-imidazole-4-carboxamide


SMILES C1C(C(C2=CC=CC=C21)NC(=O)C3=CN(C(=N3)C4=CC=CC=C4Cl)C5=CC=C(C=C5)Cl)O
InChIKey AQLBSQIWQHCSHE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 463.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pKi 7.66 7.87 8.2 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 5.29 5.61 5.92 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database