Biased Signaling Atlas

desmopressin

Agent/drug
Bioactivity

desmopressin

SMILES	N=C(N)NCCC[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSCCC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)NCC(N)=O
InChIKey	NFLWUMRGJYTJIN-PNIOQBSNSA-N

Chemical Properties

Hydrogen bond acceptors	15
Hydrogen bond donors	14
Rotatable bonds	19
Molecular weight (Da)	1068.4

Database connections

PubChem ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

No bioactivity data available.

desmopressin

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Distribution across phases (no. indications)

Phase I 3

Phase II 12

Phase III 6

Phase IV 12

Database connections

PubChem ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

Sankey plot

Drug Information

Search:

Target					Disease

Gene	Protein	Receptor family	Ligand type	Class	Name	Phase	ICD11	ATC	Association score

V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Central diabetes insipidus	4	5A61.5	H01B	0.566
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Enuresis, unspecified	4	6C00.Z	H01B	0.586
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Intracerebral haemorrhage, site unspecified	2	8B00.Z	H01B	0.092
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Leptospirosis	3	1B91	H01B	0.074
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Malignant neoplasms of breast, unspecified	2	2C6Z	H01B	0.074
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Malignant neoplasms of prostate, unspecified	1	2C82.Z	H01B	0.018
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Nasal congestion	4	MD11.9	H01B	0.565
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Overactive bladder	2	GC50.0	H01B	0.074
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Renal colic	3	MF56	H01B	0.259
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Superficial injury of unspecified body region	2	ND56.0	H01B	0.092
V1AR	V_1A receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Von Willebrand disease	4	3B12	H01B	0.462
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Central diabetes insipidus	4	5A61.5	H01B	0.566
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Enuresis, unspecified	4	6C00.Z	H01B	0.586
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Intracerebral haemorrhage, site unspecified	2	8B00.Z	H01B	0.092
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Leptospirosis	3	1B91	H01B	0.074
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Malignant neoplasms of breast, unspecified	2	2C6Z	H01B	0.074
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Malignant neoplasms of prostate, unspecified	1	2C82.Z	H01B	0.018
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Nasal congestion	4	MD11.9	H01B	0.565
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Overactive bladder	2	GC50.0	H01B	0.074
V1BR	V_1B receptor	Vasopressin and oxytocin receptors	Peptide receptors	A	Renal colic	3	MF56	H01B	0.259

Showing 1 to 20 of 33 entries

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desmopressin

desmopressin

Chemical Properties

Database connections

No bioactivity data available.

desmopressin

Drug properties

Distribution across phases (no. indications)

Database connections

Sankey plot

Drug Information