CHEMBL50056


SMILES CC(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
InChIKey DFCJPPDAOZROBS-DZUOILHNSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 7.43 7.45 7.46 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.54 5.83 6.11 ChEMBL
MC4 MC4R Human Melanocortin A pKi 6.55 6.58 6.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC5 MC5R Mouse Melanocortin A pEC50 6.66 6.95 7.16 ChEMBL
MC1 MSHR Mouse Melanocortin A pEC50 5.11 5.34 5.63 ChEMBL
MC3 MC3R Mouse Melanocortin A pEC50 5.36 5.64 6.02 ChEMBL
MC4 MC4R Mouse Melanocortin A pEC50 5.68 5.76 5.92 ChEMBL
MC1 MSHR Human Melanocortin A pEC50 7.85 7.87 7.89 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 6.61 6.69 6.77 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 7.22 7.22 7.23 ChEMBL