L-748337


SMILES O[C@H](COc1cccc(c1)CNC(=O)C)CNCCc1ccc(cc1)NS(=O)(=O)c1ccccc1
InChIKey AWIONHVPTYTSHZ-DEOSSOPVSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 13
Molecular weight (Da) 497.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β3 ADRB3 Human Adrenoceptors A pKi 8.0 8.2 8.4 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
β1 ADRB1 Human Adrenoceptors A pEC50 6.05 6.05 6.05 ChEMBL
β2 ADRB2 Human Adrenoceptors A pEC50 4.63 4.63 4.63 ChEMBL
β3 ADRB3 Human Adrenoceptors A pEC50 7.92 7.92 7.92 ChEMBL