Biased Signaling Atlas

oxtriphylline

Agent/drug
Bioactivity

oxtriphylline

SMILES	C[N+](C)(C)CCO.Cn1c2ncnc-2c([O-])n(C)c1=O
InChIKey	SOELXOBIIIBLRJ-UHFFFAOYSA-M

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	2
Molecular weight (Da)	283.3

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

No bioactivity data available.

oxtriphylline

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	Yes

Clinical Trials

Phase I 4

Phase II 16

Phase III 16

Approved Yes

Database connections

ChEMBL_compound_ids PubChem DrugBank PubChem GPCRdb

Sankey plot

Drug Information

Search:

Target					Disease				Phase

Gene	Protein	Receptor family	Ligand type	Class	Indication name	ICD11	ATC	Association score	Phase	Approved

AA1R	A₁ receptor	Adenosine receptors	Nucleotide receptors	Class A	Acute kidney failure, stage unspecified	GB60.Z	R03D	0.516	3	Yes
AA1R	A₁ receptor	Adenosine receptors	Nucleotide receptors	Class A	Asthma	CA23	R03D	0.699	4	Yes
AA1R	A₁ receptor	Adenosine receptors	Nucleotide receptors	Class A	Cardiac arrest, unspecified	MC82.Z	R03D	0.095	2	Yes
AA1R	A₁ receptor	Adenosine receptors	Nucleotide receptors	Class A	Chronic bronchitis, unspecified	CA20.1Z	R03D	0.462	4	Yes
AA1R	A₁ receptor	Adenosine receptors	Nucleotide receptors	Class A	Chronic obstructive pulmonary disease, unspecified	CA22.Z	R03D	0.566	4	Yes
AA1R	A₁ receptor	Adenosine receptors	Nucleotide receptors	Class A	Depressive disorders, unspecified	6A7Z	R03D	0.018	1	Yes
AA1R	A₁ receptor	Adenosine receptors	Nucleotide receptors	Class A	Diseases of the urinary system, unspecified	GC2Z	R03D	0.074	2	Yes
AA1R	A₁ receptor	Adenosine receptors	Nucleotide receptors	Class A	Headache, not elsewhere classified	MB4D	R03D	0.549	3	Yes
AA1R	A₁ receptor	Adenosine receptors	Nucleotide receptors	Class A	Leukaemia, unspecified	2B33.4	R03D	0.083	2	Yes
AA1R	A₁ receptor	Adenosine receptors	Nucleotide receptors	Class A	Other specified effects of air pressure or water pressure	NF04.Y	R03D	0.091	3	Yes
AA1R	A₁ receptor	Adenosine receptors	Nucleotide receptors	Class A	Pseudohypoparathyroidism	5A50.1	R03D	0.099	2	Yes
AA1R	A₁ receptor	Adenosine receptors	Nucleotide receptors	Class A	Respiratory failure	CB41	R03D	0.259	3	Yes
AA2AR	A_2A receptor	Adenosine receptors	Nucleotide receptors	Class A	Acute kidney failure, stage unspecified	GB60.Z	R03D	0.516	3	Yes
AA2AR	A_2A receptor	Adenosine receptors	Nucleotide receptors	Class A	Asthma	CA23	R03D	0.602	4	Yes
AA2AR	A_2A receptor	Adenosine receptors	Nucleotide receptors	Class A	Cardiac arrest, unspecified	MC82.Z	R03D	0.096	2	Yes
AA2AR	A_2A receptor	Adenosine receptors	Nucleotide receptors	Class A	Chronic bronchitis, unspecified	CA20.1Z	R03D	0.462	4	Yes
AA2AR	A_2A receptor	Adenosine receptors	Nucleotide receptors	Class A	Chronic obstructive pulmonary disease, unspecified	CA22.Z	R03D	0.552	4	Yes
AA2AR	A_2A receptor	Adenosine receptors	Nucleotide receptors	Class A	Depressive disorders, unspecified	6A7Z	R03D	0.048	1	Yes
AA2AR	A_2A receptor	Adenosine receptors	Nucleotide receptors	Class A	Diseases of the urinary system, unspecified	GC2Z	R03D	0.039	2	Yes
AA2AR	A_2A receptor	Adenosine receptors	Nucleotide receptors	Class A	Headache, not elsewhere classified	MB4D	R03D	0.551	3	Yes

Showing 1 to 20 of 48 entries

Join us

Cite us

Main reference

oxtriphylline

oxtriphylline

Chemical Properties

Database connections

No bioactivity data available.

oxtriphylline

Drug properties

Clinical Trials

Database connections

Sankey plot

Drug Information