CHEMBL64605


SMILES CSCC[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(N)=O
InChIKey DDROKKYSSQPXQO-FWEHEUNISA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Rat Cholecystokinin A pKi 8.03 8.03 8.03 ChEMBL
CCK1 CCKAR Guinea pig Cholecystokinin A pKi 4.92 4.92 4.92 ChEMBL
CCK2 GASR Human Cholecystokinin A pKi 7.38 7.38 7.38 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCK2 GASR Rat Cholecystokinin A pEC50 9.0 9.0 9.0 ChEMBL
CCK2 GASR Rat Cholecystokinin A pIC50 7.6 7.6 7.6 ChEMBL
CCK1 CCKAR Guinea pig Cholecystokinin A pIC50 5.75 5.75 5.75 ChEMBL
CCK1 CCKAR Rat Cholecystokinin A pIC50 5.75 5.75 5.75 ChEMBL
CCK2 GASR Human Cholecystokinin A pIC50 7.6 7.6 7.6 ChEMBL
CCK2 GASR Human Cholecystokinin A pEC50 7.89 7.89 7.89 ChEMBL