L-798,106


SMILES COc1ccc(cc1S(=O)(=O)NC(=O)/C=C/c1ccccc1Cc1ccc2c(c1)cccc2)Br
InChIKey ODTKFNUPVBULRJ-NTCAYCPXSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 535.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP3 PE2R3 Human Prostanoid A pKi 7.77 8.73 9.68 Guide to Pharmacology
EP3 PE2R3 Human Prostanoid A pKi 8.16 8.69 9.22 ChEMBL
EP1 PE2R1 Human Prostanoid A pKi 4.41 4.41 4.41 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 6.05 6.05 6.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database