BROMOCRIPTINE,(+)


SMILES CC(C)CC1C(=O)N2CCCC2C3(N1C(=O)C(O3)(C(C)C)NC(=O)C4CN(C5CC6=C(NC7=CC=CC(=C67)C5=C4)Br)C)O
InChIKey OZVBMTJYIDMWIL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 5
Molecular weight (Da) 653.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 5.68 5.68 5.68 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 8.09 8.09 8.09 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.6 7.6 7.6 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 8.15 8.15 8.15 PDSP Ki database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 5.33 5.33 5.33 PDSP Ki database
D2 DRD2 Bovine Dopamine A pKi 8.6 8.6 8.6 PDSP Ki database
D1 DRD1 Bovine Dopamine A pKi 6.97 6.97 6.97 PDSP Ki database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 6.93 6.93 6.93 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database