PP, rat


SMILES C1C(CC2=CC=CC=C2C1C3=C(OC4=CC=CC=C4C3=O)O)C5=CC=C(C=C5)C6=CC=CC=C6
InChIKey NZOWVZVFSVRNOR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 444.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y4 NPY4R Human Neuropeptide Y A pKi 9.74 9.95 10.15 PDSP Ki database
Y2 Q9ERC0 Rat Neuropeptide Y A pKi 6.0 6.0 6.0 PDSP Ki database
Y5 NPY5R Human Neuropeptide Y A pKi 6.36 6.36 6.36 PDSP Ki database
Y5 NPY5R Rat Neuropeptide Y A pKi 6.53 7.65 9.22 PDSP Ki database
Y4 NPY4R Rat Neuropeptide Y A pKi 11.57 11.57 11.57 PDSP Ki database
Y2 NPY2R Chicken Neuropeptide Y A pKi 6.0 6.0 6.0 PDSP Ki database
Y1 NPY1R Human Neuropeptide Y A pKi 6.33 6.33 6.33 PDSP Ki database
Y1 NPY1R Rat Neuropeptide Y A pKi 7.04 7.04 7.04 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database