Secoverine


SMILES CCN(CCCC(=O)C1CCCCC1)C(C)CC2=CC=C(C=C2)OC
InChIKey WAVYHSURRZBQKO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 345.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M4 ACM4 Rat Acetylcholine (muscarinic) A pKi 8.11 8.11 8.11 PDSP Ki database
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 8.23 8.54 8.85 PDSP Ki database
M2 ACM2 Rat Acetylcholine (muscarinic) A pKi 8.86 8.86 8.86 PDSP Ki database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 9.28 9.29 9.31 PDSP Ki database
M4 ACM4 Chicken Acetylcholine (muscarinic) A pKi 9.44 9.44 9.44 PDSP Ki database
M3 ACM3 Rat Acetylcholine (muscarinic) A pKi 8.28 8.28 8.28 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database