(+)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
SMILES | C1CC(C2C1C2C(=O)O)(C(=O)O)N |
InChIKey | VTAARTQTOOYTES-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 3 |
Rotatable bonds | 2 |
Molecular weight (Da) | 185.1 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
mGlu2 | GRM2 | Rat | Metabotropic glutamate | C | pKi | 7.1 | 7.58 | 8.05 | PDSP Ki database |
mGlu3 | GRM3 | Human | Metabotropic glutamate | C | pKi | 6.9 | 6.9 | 6.9 | PDSP Ki database |
mGlu2 | GRM2 | Human | Metabotropic glutamate | C | pKi | 7.07 | 7.07 | 7.07 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |