RABEPRAZOLE


SMILES COCCCOc1ccnc(C[S+]([O-])c2nc3ccccc3[nH]2)c1C
InChIKey YREYEVIYCVEVJK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 359.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 6.1 6.1 6.1 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.1 6.1 6.1 ChEMBL
A3 AA3R Human Adenosine A pKi 5.74 5.74 5.74 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 8.29 8.29 8.29 Drug Central
α2B ADA2B Human Adrenoceptors A pKi 8.21 8.21 8.21 Drug Central
D3 DRD3 Human Dopamine A pKi 8.21 8.21 8.21 Drug Central
A3 AA3R Human Adenosine A pKi 8.24 8.24 8.24 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pIC50 5.76 5.76 5.76 ChEMBL
D3 DRD3 Human Dopamine A pIC50 5.63 5.63 5.63 ChEMBL
A3 AA3R Human Adenosine A pIC50 5.49 5.49 5.49 ChEMBL