SIB-1757


SMILES CC1=NC(=C(C=C1)O)N=NC2=CC=CC=C2
InChIKey LOCPVWIREQIGNQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 213.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Human Metabotropic glutamate C pKi 5.96 6.3 6.48 PDSP Ki database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 5.93 6.23 6.46 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database